porducts list
- Other [10]
contact datails
Chembest Bioscience Inc.
Mr Bruce Leung
No.9300,Hunan Highway,Pudong,Shanghai,China
86 -21-20908456
Mr Bruce Leung
No.9300,Hunan Highway,Pudong,Shanghai,China
86 -21-20908456
| Chemical name:5-[2,5-Dihydro-2-[[4-(4-morpholinyl)phenyl]imino]-4-pyrimidinyl]-4-methyl-2-thiazolamine Biological Activity: CYC116 (CYC-116)is an oral small molecule Aurora kinase/VEGFR2 inhibitor with antineoplastic activity. It inhibits Aurora kinases A and B and VEGFR2, resulting in disruption of the cell cycle, rapid cell death, and the inhibition of angiogenesis. CYC116(CYC-116) has a unique target profile involving both cell cycle and angiogenesis inhibition mechanisms. In preclinical studies, it demonstrated antitumor activity in both solid tumors and hematological cancers. |
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